Many of my friends think that prices of products is generally cheaper in Johor Bahru than in Singapore. Well, it is true to a certain extent but it depends on what products you are buying. For example, I wouldn't want to buy branded sports shoes in Johor Bahru; as you can also get it at the same price or even lower in Singapore. And the styles of shoes are more updated in Singapore. In fact during the Great Singapore Sale, many items such as clothes, digital products, shoes, watches, jewellery and even food items are a great buy in Singapore.
Some of my friends will go to Johor Bahru to buy daily necessities such as cooking oil, sugar, milk, detergent, toiletries, food products etc. I think these products are generally cheaper in Johor Bahru. I know that prices of medicine is cheaper in Johor Bahru; and you don't even need a doctor prescription for many medicines sold at the Pharmacies over there. That is why Singaporeans especially the old folks who need to take daily medicine to control their ailments such as cholesterol or blood pressure will buy medicine in Johor Bahru.
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Take for example the commonly used Eye drop from Eye Mo. The retail price for this product in Singapore is about S$5/- onwards. In Johor Bahru the retail price for this item is approx. RM7. If you convert it to Singapore dollars, this item is sold for $3/- only. There is a saving of $2 if you buy this item in Johor Bahru.
So be a smart shopper by listing down the brand, item, price and the packaging size of the products that you what to buy in Johor Bahru. Do a comparison while you are in Johor Bahru and determined the savings. If the savings is nominal, then just buy it in Singapore. Anyway, Johor Bahru is a great place to eat delicious food at much lower cost than in Singapore; so enjoy the food while you are there.